Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Silodosin is an alpha-1A blocker: it relaxes the smooth muscle of the prostate and bladder neck, making it easier to pass urine. It is used for the urinary symptoms of an enlarged prostate (benign prostatic hyperplasia) and sometimes to help pass kidney stones. A common side effect is reduced or absent ejaculation. It is sold as Rapaflo, Urorec and Silodyx.
Silodosin is broken down mainly by CYP3A4 and by UGT2B7, which joins it to glucuronic acid. The few gene studies on it looked at CYP3A4 and UGT2B7 variants for its blood levels. The findings come from a few studies, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Silodosin. Upload your DNA file to see which of these rows apply to you.
Studies of how quickly the body processes this medication.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Advair (Corticosteroid + LABA)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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