Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Mirabegron is a beta-3 adrenergic agonist: it relaxes the bladder muscle during filling, so the bladder holds more urine. It is used for overactive bladder, with urgency, frequent urination and leakage, and in children for a bladder problem caused by nerve damage. It is sold as Myrbetriq and Betmiga.
Mirabegron is cleared by several routes, including the liver enzymes CYP3A4 and CYP2D6. People with no working CYP2D6 copies (poor metabolizers) have modestly higher levels, which the US FDA lists as an effect on drug levels; mirabegron also blocks CYP2D6 itself. There is no CPIC or DPWG guideline, and the few other studies on this page are single findings.
Clinical guidelines that name a gene for Mirabegron. They sort people into groups by the gene copies they carry.
Every published finding on gene variants and Mirabegron. Upload your DNA file to see which of these rows apply to you.
Studies of how quickly the body processes this medication.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
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Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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