Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Gemigliptin is a DPP-4 inhibitor developed in South Korea: it blocks the enzyme that breaks down incretins, gut hormones that make the pancreas release insulin after a meal. It is used for type 2 diabetes in Korea and several other countries, and is not approved in Europe or the US. It is sold as Zemiglo.
Gemigliptin is cleared partly by CYP3A4 and partly unchanged by the kidneys. The gene study listed, from Korea, looked at GLP1R for how much blood sugar fell. The evidence is weak, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Gemigliptin. Upload your DNA file to see which of these rows apply to you.
Studies of how well it worked in people carrying a variant.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
DPP-4 Inhibitors (class) (DPP-4 Inhibitors)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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