Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Valsartan is an angiotensin II receptor blocker (ARB): it stops angiotensin II from narrowing blood vessels and making the body hold salt. It is used for high blood pressure, heart failure and after a heart attack, and combined with sacubitril (Entresto) for heart failure with reduced pumping. It is sold as Diovan, among other names.
Valsartan is barely broken down; it is excreted mostly unchanged in bile, taken into the liver by SLCO1B1 and SLCO1B3. The gene study listed looked at AGT, the angiotensinogen gene, for blood pressure response. The evidence is weak, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Valsartan. Upload your DNA file to see which of these rows apply to you.
Studies of how well it worked in people carrying a variant.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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