Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Talinolol is a beta-1 selective beta blocker that was used in Germany for high blood pressure and heart rhythm problems under the name Cordanum. It is now mainly known as a research tool: because it is barely broken down and moved almost entirely by transporters, it is used to study the drug pump P-glycoprotein (ABCB1) in the gut.
Talinolol is hardly broken down by enzymes; its absorption and clearance depend on the transporters ABCB1, ABCC2 and ABCG2. Studies, mostly in healthy volunteers, linked variants in these transporter genes to its blood levels. There is no CPIC or DPWG guideline.
Every published finding on gene variants and Talinolol. Upload your DNA file to see which of these rows apply to you.
PharmGKB weighs all studies of a variant and rates how strong the evidence is, from 1A (strongest) to 4.
ABCC2 rs2273697: Level 3. Metabolism/PK. 2.
ABCB1 rs1045642: Level 3. Other. 1.
Studies of how quickly the body processes this medication.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Beta Blockers (class) (Beta Blockers)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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