Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Lacidipine is a long-acting calcium channel blocker of the dihydropyridine group: it relaxes the muscle of artery walls, so they widen and blood pressure falls. It is used once daily for high blood pressure in Europe and Asia; it is not marketed in the US. It is sold as Motens and Lacipil, among other names.
Lacidipine is broken down mainly by CYP3A4. The gene studies on it, from China, looked at the calcium channel gene CACNA1C, the target of the medicine, for how much blood pressure fell. The findings come from a few studies, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Lacidipine. Upload your DNA file to see which of these rows apply to you.
Studies of how well it worked in people carrying a variant.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Calan (Calcium Channel Blockers)
Calcium Channel Blockers (class) (Calcium Channel Blockers)
Cardene (Calcium Channel Blockers)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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