Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Hepatitis vaccines protect against viral hepatitis. Hepatitis B vaccines contain the virus's surface protein and are given in two to four doses, often from birth; hepatitis A vaccines contain inactivated virus and are given in two doses, for example before travel. Some combined vaccines cover both.
About 5 to 10 in 100 healthy adults make few antibodies after the standard hepatitis B vaccine course. Studies linked this to immune-system gene versions, especially HLA-DRB1 and HLA-DQ types, and to IL4R and IL13, genes of the antibody response. The findings come from a few studies, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Hepatitis Vaccine. Upload your DNA file to see which of these rows apply to you.
PharmGKB weighs all studies of a variant and rates how strong the evidence is, from 1A (strongest) to 4.
IL13 rs1295686: Level 3. Efficacy. 1.
IL4R rs1805015: Level 3. Efficacy. 1.
Studies of how well it worked in people carrying a variant.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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