Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Cefalexin (cephalexin) is a first-generation cephalosporin antibiotic taken by mouth, which blocks bacteria from building their cell wall. It is widely used for skin and soft tissue infections, urinary tract infections, strep throat and bone infections. It is sold as Keflex, among other names.
Cefalexin is not broken down; it is absorbed by the gut peptide transporter and cleared unchanged by the kidneys. PharmGKB lists a single low-rated finding, on allergic reactions. There is no CPIC or DPWG guideline.
Every published finding on gene variants and Cephalexin. Upload your DNA file to see which of these rows apply to you.
PharmGKB weighs all studies of a variant and rates how strong the evidence is, from 1A (strongest) to 4.
rs34545984: Level 3. Toxicity: adverse events. 1.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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