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Celiprolol

Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.

About Celiprolol

What it is

Celiprolol is a beta blocker that blocks beta-1 receptors on the heart while mildly activating beta-2 receptors, which widens blood vessels. It is used for high blood pressure and angina in several European countries, and has been studied for vascular Ehlers-Danlos syndrome; it is not marketed in the US. It is sold as Celectol, among other names.

How genes come into it

Celiprolol is hardly broken down; its absorption from the gut depends on the transporters SLCO1A2 and ABCB1, and it is cleared largely unchanged. The few gene studies on it looked at SLCO1A2 and ABCB1 for its blood levels, and at KCNH2. The findings come from a few studies, and there is no CPIC or DPWG guideline.

What research found

Every published finding on gene variants and Celiprolol. Upload your DNA file to see which of these rows apply to you.

Metabolism (2 findings)

Studies of how quickly the body processes this medication.

ABCB1 rs1045642: Allele G is associated with decreased concentrations of Celiprolol in healthy individuals as compared to allele A.

SLCO1A2 rs11568563: Allele G is associated with decreased concentrations of Celiprolol in healthy individuals as compared to allele T.

Response (1 finding)

Studies of how well it worked in people carrying a variant.

KCNH2 rs1137617: Genotype GG is associated with response to atenolol, bisoprolol, Celiprolol or doxazosin in people with Essential hypertension as compared to genotypes AA + AG.

Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.

Related Drugs

More drugs from the same category

Beta Blockers (class) (Beta Blockers)

Betapace (Beta Blockers)

Bucindolol (Beta Blockers)

Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.

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Content updated September 2026.

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