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Zinc Acetate (Galzin)

Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.

About Zinc Acetate

What it is

Zinc acetate is a zinc salt used as a medicine. As Galzin (Wilzin), it is a maintenance treatment for Wilson's disease: zinc makes gut cells produce metallothionein, which traps copper so it is lost in the stool instead of absorbed. Zinc acetate lozenges are also sold for colds.

How genes come into it

Zinc is absorbed and handled by zinc transporters rather than drug-processing enzymes. The gene study listed looked at SLC30A8, a zinc transporter in insulin-making cells and a type 2 diabetes gene, for blood sugar response to zinc supplements. The evidence is weak, and there is no CPIC or DPWG guideline. Wilson's disease itself is caused by ATP7B variants.

What research found

Every published finding on gene variants and Zinc Acetate. Upload your DNA file to see which of these rows apply to you.

Rated evidence (1 rated variant)

PharmGKB weighs all studies of a variant and rates how strong the evidence is, from 1A (strongest) to 4.

SLC30A8 rs13266634: Level 3. Efficacy. 1.

Response (1 finding)

Studies of how well it worked in people carrying a variant.

SLC30A8 rs13266634: Genotypes CT + TT is associated with increased response to insulin recombinant and zinc acetate in healthy individuals as compared to genotype CC.

Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.

Related Drugs

More drugs from the same category

Actos (Thiazolidinediones)

Amaryl (Sulfonylureas)

Antithyroid Drugs (class) (Antithyroid Agents)

Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.

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Content updated September 2026.

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