Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Tildrakizumab is a biologic medicine, a monoclonal antibody that blocks the p19 part of interleukin-23, a signal that drives the inflammation in psoriasis. Injected every twelve weeks after two starting doses, it is used for moderate to severe plaque psoriasis. It is sold as Ilumya and Ilumetri.
As an antibody, tildrakizumab is not broken down by drug-processing enzymes. The few gene studies on it, from one study of psoriasis patients, looked at immune genes such as TNFAIP3, IL17RC, ATG5 and PDE4D for who responded. The findings have not been confirmed, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Tildrakizumab. Upload your DNA file to see which of these rows apply to you.
Studies of how well it worked in people carrying a variant.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Aldara (Immune Response Modifiers)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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