Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Sympathomimetics are medicines that mimic the effects of adrenaline and noradrenaline on the sympathetic nervous system. They include adrenaline for anaphylaxis, noradrenaline, dopamine and dobutamine for shock, phenylephrine and pseudoephedrine as decongestants, and beta-2 agonists such as salbutamol for asthma. This page collects studies on them as a group.
The single gene study listed for the group looked at OPRM1 in the context of side effects. Gene findings for individual sympathomimetics, such as ADRB2 for the beta-2 agonists or ADRB1 for dobutamine, are on their own pages. There is no CPIC or DPWG guideline.
Every published finding on gene variants and Sympathomimetics. Upload your DNA file to see which of these rows apply to you.
PharmGKB weighs all studies of a variant and rates how strong the evidence is, from 1A (strongest) to 4.
OPRM1 rs1799971: Level 3. Toxicity: Cardiac Arrest, Overdose, Respiratory Insufficiency. 1.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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