Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Sulfinpyrazone is a uricosuric medicine: it blocks the reabsorption of uric acid in the kidney, so more uric acid leaves in the urine. It was used for long-term treatment of gout and, because it also inhibits platelets, was studied after heart attacks. It has largely been replaced by other medicines and is no longer marketed in many countries. It was sold as Anturane.
Sulfinpyrazone is broken down partly by the enzyme UGT1A9, and a single study looked at UGT1A9 variants for its clearance. It is also a strong blocker of CYP2C9, which affects other medicines such as warfarin. There is no CPIC or DPWG guideline.
Every published finding on gene variants and Sulfinpyrazone. Upload your DNA file to see which of these rows apply to you.
PharmGKB weighs all studies of a variant and rates how strong the evidence is, from 1A (strongest) to 4.
UGT1A9 rs72551330: Level 3. Metabolism/PK. 1.
Studies of how quickly the body processes this medication.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Aldara (Immune Response Modifiers)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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