Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Rifapentine is a long-acting relative of rifampicin: it blocks bacterial RNA polymerase. Taken once a week together with isoniazid for twelve weeks (the 3HP regimen), or daily for one month, it treats latent tuberculosis infection, and it is used in some regimens for active tuberculosis. It is sold as Priftin.
Rifapentine is cleared mainly by esterases and excreted in bile. The few gene studies listing it looked at ABCB1 for its levels and at NAT2, which concerns the isoniazid it is combined with. The findings come from a few studies, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Rifapentine. Upload your DNA file to see which of these rows apply to you.
Studies of how quickly the body processes this medication.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Isoniazid (Antimycobacterials)
Myambutol (Antimycobacterials)
Pyrazinamide (Antimycobacterials)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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