Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
L-ornithine is an amino acid that takes part in the urea cycle, the liver's route for turning ammonia into urea. Combined with aspartate (L-ornithine L-aspartate, Hepa-Merz), it is used in some European and Asian countries to lower ammonia in hepatic encephalopathy, brain effects of advanced liver disease. It is also sold as a supplement.
Ornithine is handled by the body's normal amino acid pathways, not by drug-processing enzymes. The gene study listed looked at NPC2. The evidence is weak, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and L-Ornithine. Upload your DNA file to see which of these rows apply to you.
Studies of how quickly the body processes this medication.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Antithyroid Drugs (class) (Antithyroid Agents)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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