Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Recombinant human insulin is insulin made by genetically modified bacteria or yeast, identical to the hormone the pancreas makes. Injected under the skin, it lets cells take up glucose and lowers blood sugar. It is essential in type 1 diabetes and used in type 2 diabetes, gestational diabetes and emergencies. Short-acting (regular) and intermediate (NPH) forms exist, sold as Humulin, Novolin, Actrapid and others.
Insulin is broken down mainly by insulin-degrading enzyme in the liver and kidneys, not by drug-processing enzymes. The gene study listed looked at SLC30A8, a zinc transporter in insulin-making cells and a type 2 diabetes gene, for response. The evidence is weak, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Insulin. Upload your DNA file to see which of these rows apply to you.
PharmGKB weighs all studies of a variant and rates how strong the evidence is, from 1A (strongest) to 4.
SLC30A8 rs13266634: Level 3. Efficacy. 1.
Studies of how well it worked in people carrying a variant.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Antithyroid Drugs (class) (Antithyroid Agents)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
ReadYourDNA provides educational interpretation of DNA data you already have. It is not diagnostic, not a substitute for professional medical advice, diagnosis, or treatment, and is not intended to diagnose, treat, cure, or prevent any disease. Talk to a clinician before acting on any result.
Raw DNA Data Reports for 23andMe & AncestryDNA · About ReadYourDNA · FAQ · Methodology & Science · Pricing · Support and complaints · Legal & Contact · Health Traits · Pharmacogenomics · Carrier Status · Variant Explorer · The Human Karyotype · Privacy Policy · Terms of Service · Accessibility · Consumer Health Data Privacy · Your Privacy Choices · Editorial Standards · Your Data, Checkable · Sample Report · ReadYourDNA and Promethease compared · What is inside a 23andMe raw data file · What is inside an AncestryDNA raw data file · What a chatbot can and cannot do with your raw DNA file · Where a raw DNA file can still be uploaded in 2026
Written, maintained and operated by Martin Pechhacker, sole proprietor, Vienna, Austria. Trade register GISA 40064420. support@readyourdna.com