Fenoterol (Berotec)

Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.

About Fenoterol

What it is

Fenoterol is a short-acting beta-2 agonist that relaxes airway smooth muscle. It is used as an inhaled reliever for asthma and COPD, often combined with ipratropium (Berodual), in Europe and other regions; it is not marketed in the US. It is sold as Berotec.

How genes come into it

Fenoterol is cleared mainly by sulphate and glucuronide conjugation. The gene studies on it, from volunteer studies in Germany, found that SLC22A1 (OCT1) carries fenoterol into the liver, and that people with low-function OCT1 versions had higher blood levels and stronger effects on heart rate and blood sugar. There is no CPIC or DPWG guideline.

What research found

Every published finding on gene variants and Fenoterol. Upload your DNA file to see which of these rows apply to you.

Metabolism (5 findings)

Studies of how quickly the body processes this medication.

SLC22A1 rs12208357: Allele T are associated with increased exposure to fenoterol in healthy individuals as compared to allele C.

SLC22A1 rs34059508: Allele A are associated with increased exposure to fenoterol in healthy individuals as compared to allele G.

SLC22A1 rs34130495: Allele A are associated with increased exposure to fenoterol in healthy individuals as compared to allele G.

SLC22A1 rs55918055: Allele C are associated with increased exposure to fenoterol in healthy individuals as compared to allele T.

Other findings (1 finding)

Studies that do not fall into the groups above.

SLC22A1 rs1349294037: Genotype TAAGTTGT/TAAGTTGT is not associated with increased concentrations of fenoterol as compared to genotype del/del.

Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.

Related Drugs

More drugs from the same category

Beta-2 Agonists (class) (Beta-2 Agonists)

Brethine (Beta-2 Agonists)

Foradil (Beta-2 Agonists)

Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.

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Content updated September 2026.

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