Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Ulinastatin is a protease inhibitor protein purified from human urine (urinary trypsin inhibitor). It blocks trypsin and other enzymes released in inflammation. It is used by injection in Japan, China, Korea and India for acute pancreatitis, sepsis and circulatory shock, and during some surgeries; it is not approved in Europe or the US.
As a protein, ulinastatin is not handled by drug-processing enzymes. The few gene studies listed, from China, looked at MMP2 and MMP9, enzymes that break down tissue during inflammation, for how well it worked. The findings come from a few studies, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Ulinastatin. Upload your DNA file to see which of these rows apply to you.
Studies of how well it worked in people carrying a variant.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Agenerase (Protease Inhibitors)
Crixivan (Protease Inhibitors)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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