Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.
Sarilumab is a biologic medicine, a fully human monoclonal antibody that blocks the interleukin-6 receptor, like tocilizumab. Injected every two weeks, it is used for moderate to severe rheumatoid arthritis and for polymyalgia rheumatica. It is sold as Kevzara.
As an antibody, sarilumab is not broken down by drug-processing enzymes. The gene studies on it looked at IL6R, the gene for its target receptor, for response in rheumatoid arthritis. The findings come from a few studies, and there is no CPIC or DPWG guideline.
Every published finding on gene variants and Sarilumab. Upload your DNA file to see which of these rows apply to you.
Studies of how well it worked in people carrying a variant.
Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.
More drugs from the same category
Agenerase (Protease Inhibitors)
Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.
Content updated September 2026.
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