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Antibiotics (class)

Raw research findings for this medication. Mostly single studies, not curated or confirmed robust.

About Antibiotics

What it is

Antibiotics are medicines that kill bacteria or stop them from multiplying, by attacking structures human cells do not have, such as the bacterial cell wall or ribosome. The main groups include penicillins, cephalosporins, macrolides, tetracyclines, fluoroquinolones, aminoglycosides and sulfonamides. They do not work against viruses. This page collects studies on antibiotics as a group.

How genes come into it

For antibiotics as a group there is little gene evidence; the few studies here looked at KCNE1 for heart rhythm effects and LGALS3. The firm gene links are for particular antibiotics: MT-RNR1 variants (in mitochondrial DNA) make hearing loss from aminoglycosides such as gentamicin much more likely, G6PD deficiency matters for nitrofurantoin and sulfonamides, and HLA variants for some hypersensitivity reactions. Those are covered on the pages of the individual medicines.

What research found

Every published finding on gene variants and Antibiotics. Upload your DNA file to see which of these rows apply to you.

Rated evidence (2 rated variants)

PharmGKB weighs all studies of a variant and rates how strong the evidence is, from 1A (strongest) to 4.

LGALS3 rs11125: Level 3. Toxicity: Hypersensitivity. 1.

KCNE1 rs1805128: Level 3. Toxicity. 1.

Response (1 finding)

Studies of how well it worked in people carrying a variant.

ABCB1 rs1045642: Genotype AA is associated with decreased clinical benefit to Antibiotics and esomeprazole in children with Helicobacter Infections as compared to genotypes AG + GG.

Study findings and evidence levels: PharmGKB (CC BY-SA 4.0). Guidelines: CPIC and DPWG, as bundled in PharmCAT. Most studies were done mainly in people of European ancestry.

Related Drugs

More drugs from the same category

Macrobid (Antibiotics)

Actemra (IL-6 Inhibitors)

Agenerase (Protease Inhibitors)

Not a prescribing recommendation. This page is educational information about pharmacogenomic research and clinical guidelines - it is not medical or dosing advice, and not a prediction of how any medication will work for you. Never start, stop, or change a medication or dose based on it; talk to your doctor or pharmacist, who can order clinical-grade testing if appropriate.

Back to Medications

Content updated September 2026.

ReadYourDNA provides educational interpretation of DNA data you already have. It is not diagnostic, not a substitute for professional medical advice, diagnosis, or treatment, and is not intended to diagnose, treat, cure, or prevent any disease. Talk to a clinician before acting on any result.

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